uh you could buy a pico itx board and just run uae on it. Thats what your really talking about. using a pc to emulate the 68060...
or you could get a Virtex-5 FXT FGPA ML507 that plugs into your PC's pci-e slot that has a v5 fpga and powerpc 440 core onboard with a boatload of connectors and make a fully functional hardware miggy right in your pci-e slot..