I would say a kick remapper (Blizkick or RemApollo depending on your card), BlazeWCP, Cyberpatcher or Oxypatcher for 040 or especially 060, Fblit. I found going too far with dozens of patches could cause problems. I'd avoid Executive too, tried it twice and got rid of it twice very quickly. As suggested some sort of Text speedup might help too. That's most of the bottlenecks taken care of then.
FScreen speeded up browsing enormously but it was a switch on/switch off thing because some programs (e.g. Star Trek 25th) didn't like it at all.