In terms of using them, it seems that way At least Prepcard can read the card vendor and type (if it's on the card).
Reading vendor and product data is a PCMCIA standard, it works for all cartridges independent of their purpose.
However, floppy users seem to have a problem with using large PCMCIA cards (over 2GB).
There is a hit and miss of which CF cards work or don't work. Some work on IDE only, some on PCMCIA only or all other combinations. It has nothing to do with the software configuration or the size of the CF cards. Sometimes larger CF cards even work better than smaller ones.
I can't help but thing it is not just compactflash.device involved, setpatch if the only component that is involved with the process for users with old ROMs and new hard drives,
There are patches for PCMCIA hardware bugs. See CardPatch and CardReset on Aminet. This has nothing to do with large harddrive support.
SetPatch of OS 3.5+ patches NSD support into many devices. But it does not enable large harddrive support. Only by chance if the device already supports TD64 or Direct-SCSI but not NSD-TD64.
Big (>4gb) PCMCIA card seems to be working but craps out when it is filled too much.
The opposite is true. It fails to display large sizes and thus large amounts of free space lead to erroneous "drive full" conditions.