I really like the Amiga classic look with MUI. However since different apps used different looks, workbench, MUI, classact, etc... you we're left with an inconsistent look that broke the feel of the system.
That was the main problem with OS 3.x. It really is a battle to maintain consistency.
I like Mac OS 8 with it brushed aluminium look for its simplicity and consistency.
Currently I run OS 3.9 with Boing Bag 4 and Ken's icons and the Peterk library in CGX:1280x1024:16 bit. Very nice, but I'm forever replacing application default icons with Ken's icons when I can get them