The 68060 is a little bit less Amiga game compatible than the 68040. This is mostly due to the larger instruction cache (which can be turned off or to 1/2) and the missing 64 bit integer math instructions which require the 68060.library to emulate. Most games that start from the hard drive work fine but installing the 68060.library for floppy use may be a pain. The 68060 is a great processor and much better at running 68020/68030 code than the 68040. Productivity software is very rare to have a problem with the 68060.
