Hi i am using CoolnesS. This run nes games quite good on mine. They other i use are magic64, Amimastergear. Atari800XL. mame030. There are some slowdown on the magic64 on some games.
Amimastergear and the developers other emulators are incredibly fast because they are written in assembly and seem to be highly optimised. I seem to remember playing one of the Sonic games at about 300 fps on my 060.
I never tried C64 emulation since I didn't own one back in the day it holds no nostalgia but I heard a lot of good things about Frodo so maybe that's worth a try for C64 fix.