I have in my A500+ a trumpcard 500 hdd and a derringer 030 w 32MB ram...
whats most populat... hmmm... any kind of harddrive. i guess... and maybe an accelerator.... RAM is most appreciated... and kickstart 1.3 or higher... But all depending on what you want to use your A500 for...
EDIT:
And of course, any MOD depends on availability....