Personally, I bring everything to a D9 CGA-spec connector, or HD15 VGA-spec connector for my stuff. (Multiple monitors, multiple computers and JAMMA rigs.) I started off with a custom DB25 based connector, then found it was more useful to use an already-existing standard instead.
(Yes, i use VGA HD15, but only as far as the pinout names. it might be hooked up as RGB, but it might sync lower than VGA scan rates, etc.)