pfs3 and sfs is very near each others, i used pfs3 for a long time (and before that pfs,pfs2) and i had no problems until it died...and it died bigtime! ...i switched to sfs and i am happy!
anyway i dont have a 2terrabyte big disk so i cant answer to your question , but i have a partision which is 75gb and that works fine

, have 2-3 at 40gb and some smaller ones...
i use os3.9 and sfs (worked with pfs3 also).