Go for it, it is recommended because amiga floppy drivers has a tend to fault. And the sd cards just way faster to read. If you want hard drivers, you need to buy some hd expansion card. (it is fitted to the side expansion port) Or get an accelerator hdd drive combo 2 in 1. (because some accelerator card dont' like some of the hdd cards) or 3:1 with memory upgrade.
Anyway some of the accelerator can use modern (ie 80GB or more) hard drives, but it is really depend on the actual modell. Of course most of the 90' hard drivers works, but you know, most of them not or not working correctly because of ageing.