I use AVG antivirus and ZoneAlarm firewall - they've done a good job here - both are free editions. I think I've had a few "false positives" from AVG, but that is better than a failure to detect if you ask me. I like ZoneAlarm because it lets me control what goes out as well as preventing others from getting in.
As orange says, prevention is better than cure, so if you are careful where you go then there is less risk anyway - but not nil risk these days because of drive-by attacks. I do not use Intranet Expander or Outlook anything. I think the best browser is Firefox with the NoScript add-on, but Opera is good too.
And if you never got LAMER'ed on your Amiga then you've never lived ;-)