@mel_zoom
Rendering programs, anything using a lot of ram image editors etc, sound editing progs etc. Anything that take things and applies large batch style processes to them etc.
Games etc it won't matter to in most cases, with faster new hardware you'd possibly see less chugging than on a standard amiga chipset, but you also might get the game running at many multiples of the original speed if it hadn't been coded to avoid that.
Then there's compatibility issues with emulated hardware. UAE is pretty good at dealing with most of them but there's still a few.
Andy