I can tell you that I used the latest scsi.device from the OS3.9 ROM Update to recognize a 160GB drive, though HDToolBox would only partition a 127GB partition (IIRC) and formatting only saw 7GB. (Weird.)
As for the floppy bit, ISTR that the oddity of the HD drive is due to the Amiga floppy controller having a max bit rate of 250kbps. The Amiga-compatible HD floppy drive slows the drive to 150RPM to ensure that a HD floppy bit rate stays at 250kbps.
Posit: The Amiga floppy controller is limited to 250kbps
Consequence: The Amiga requires non-standard floppy drives
Result: Using standard floppy drives requires special equipment and drivers
Conclusion: A special configuration in the forthcoming/upcoming/God-sent CloneA chipset is called for ;-)