You need either an IDE or SCSI interface for starters. Then you'd need a SCSI or IDE drive of course. After that, you'll need either AsimCDFS or AmigaOS 2.x or better so that the Amiga "sees" your drive.
There's a Zorro II IDE card that exists and is for sale through Amigakit I believe still or you can hook a SCSI CD-ROM to a 2091 card as well. Most accelerator cards for the A2000 also have SCSI built in and that's what I use with my CD-ROM. An A2091 card can be had for about $20 and same with a SCSI CD-ROM if you can find one. The Zorro II IDE board runs about $60-$80 and IDE drives are a dime a dozen.