Yeah, that did come across as a bit harsh... But yeah, I'm not a fan, the actual CPU core is pretty weak and of little use for desktop work.
The Xbox 360's CPU is better, but no AmigaOS can handle multiple cores (due to an architectural limitation, that was designed into the OS from the start), so wouldn't be much use either...
My thoughts are that If an OS can handle a single core then it can be architected to handle multiple cores. Even if it is via loosely coupled multiple OS instances running in there own segregated resource pools per task, it can still be done. With time and effort. The challenges would be around the integration of display and hardware access. But nothing different than the same challenges on virtual host OSes.
Imagine a multi threaded Amiga OS running on current CPU and GPU hardware and us doing the things that we do on Mac and PC today. Mmmm Power. I'd buy that for a dollar.