2 issues:
#1: B2000 has no clockport (unless you have a Zorro card like the Buddha IDE controller that adds one).
#2: The USB stack requires a 68020 or greater, so you'll need a CPU card. However, there is another USB stack that will work on a 68000, but is extremely limited in terms of speed and drivers.
I agree with the limitation in term of speed, but not agree for the numbers of drivers: ANAIIS is nearly 95% compatible with the Sirion API. So if a driver exists for AmigaOS4.x, it can be used with ANAIIS... if you compile it for 3.x. ANAIIS is able to manage hubs, mouse, keyboard, HID (joysticks, keyboards with special keys, mouse with extra buttons), printers, camera (not webcam, but outdated things for taking still pictures), massstorage, iPhone and iPad. What else ?
