If I had had that much RAM a few years ago when I was editing audio using my Amiga 2000, it would have come in really handy. I could have edited almost an entire CD with 450MB+ RAM at once. As it was, I had to use virtual RAM (HD RAM) and it was very slow.
Like the other fellow above said, any Amiga productivity software could benefit from that much RAM, but if all you do is play classic games, etc., then I guess that much RAM wouldn't be much use.
