I haven't found anything that Dpaint could do with animating that Brilliance couldn't. They just use a different interface to achieve the same result. brilliance also seems to load anims faster too.
Well, Brilliance doesn't do onion-skinning. If it did then I'd probably use it exclusively, because it is great.
All three programs mentioned in this thread are great and compliment each other. PPaint is also good because it supports RTG screenmodes.
