Do you see any possibility to make an acc card for "real" amiga hardware using the RPi Compute module?
This was discussed. I have no interest in doing it, the accelerator market is somewhat saturated. It's much easier to interface the compute module directly to the FPGA as you can control timing. To fit in a 68K socket you would need a bridge device so you are losing the cost benefit. Perhaps a zynq with embedded CPU core would be interesting, but they are quite pricey.
"We know that we can put APOLLO in to an ASIC."
I can put anything into an ASIC. My day job is working for a fables ASIC house that actually makes chips (specialist high performance 28nm CPUs amusingly). I keep meaning to run the TG68K CPU through the Cadence synthesiser and get a timing estimate - it would probably go at least 500Mhz, maybe more.
That doesn't mean it's going to happen though. Licence costs for the tools, cells and memory compilers are very steep, as are the production costs. We make high price devices so there is a business case. I don't see a fast 68K processor selling for more than a few$ - it's got to compete against Atmel etc who make really quite nice ARM based SOCs.
There is test, characterisation and a million other things to consider apart from having just the RTL.
NXP still make 68K devices. While making a few hobby FPGA designs is not going to interest them, they will aggressively protect their IP if you try to make a business out of it.
The vampire core is fun and seems to work well, but I don't believe it's going to take over the world (unless ARM was to vanish tomorrow).
/Mike