Here's my opinion.
Much of the fun of the Amiga is its modular nature (think multiple expansion possibilities though Zorro/clockport, which then offer further potential through PCI/USB/IDE etc cards). A clone which is a stand-alone board just wouldn't be the same. If an A4000 clone was created which was compatible with the A4000 case and still had a slot for the daughterboard and a CPU slot, then I would definitely buy one as a backup should my A4000 motherboard ever die.
Of course the board should also be improved upon, with SATA ports etc.
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moto