I had the same problem. I was getting a guru on bootup on ocassion, other times on bootup I would get a recoverable alert! A few times it would get to the Workbench screen and just lockup. However, sometimes it would bootup fine.
Anyway, I went back to the last version of Setpatch and all seems to be fine.
I also downloaded the patch just fine with IB2.2 in reply to some of the other posts.
A3000T 64MB WarpEngine040/40Mhz PicassoII
GVP/IO
AradneII
2 Sunrize AD516s
Yamaha CDRW
yadda yadda yadda :-)