I have a couple of Vampires, they are good with productivity as long as you don't need an FPU. Continuous work on the core offers a good deal of compatibility with WHDLOAD games. The integer performance of the 68080 outlcasses any Amiga FPU option. So if possible run the integer version.
They are continuously updating the core... I can tell you that they are on it every day.
With all the other amenities you get (HDMI, Faster IDE, SD card slot with network capability) you simply can't find a better value even if there isn't an FPU. It is my understanding they want to improve the 68080 as it's the Central Processor, the brains of the system and has greater priority then do FPU work. They are also doing other things related to Amiga hardware components related to display hardware.
If you want max compatibility or "real" hardware check on Amibay for a good 040 / 060 card and a picasso card and a flicker fixer.
Vampire is a long term project but at least the CPU "hardware" upgrades consist of a "free core software download" instead of a trip to EBAY / Amibay.