How does the MCC-216 with its Amiga core fit in with these machines?[/url]
It would be best to wait for the next non-beta version of the MCC-216 Amiga core. With the present version, you will even have problems starting SysInfo since it frequently locks up when accessing the "disk".
Future version might of course have turbo-options (like the C64 already has). The Cyclone 3 they are using surely has some reserves regarding clock rates.