It is known that Apollo accelerators have timing problems with some Amiga 1200 motherboards and cause frequent crashes. I can't remember which revisions are affected, but if you do a search here, you will find them.
It was revision 1D4 (the most common one) which was most affected by timing problems.
However, you can't bet on that. My 1D4 has been running perfectly so far with all accelerators I plugged in.