I dont know what i would do personally but i'd love to see a nice classic Amiga based motherboard that can be put in a standard ATX case.
The specs i'd like to see would be:
Basic 68030 CPU + AGA Chipset with:
Optional or standard G4 CPU (obviously compliant with OS4)
A socket for a 68040 or 68060 CPU
Can address DDR2/3 Ram as fast ram with sockets
Has built in a Picasso96 compliant graphics card which shares memory
Built in USB and Ethernet ports
Built in Sata
PCI Slots
Maybe a floppy drive port which can use normal 1.44MB PC drives as 1.76mb Amiga