A nice idea would be a cloned A1200 motherboard which can fit inside the A1200's original casing replacing the original motherboard.
A nice spec would be:
68030 @ 50Mhz (with an option to upgrade using a real 68060)
32bit memory (Like on accelerator boards) upgradable with standard DDR/2 ram
Built in USB + LAN/Wifi (original A1200 case would need modding)
2 Fast IDE connectors
Support for PC floppy drives including HD drives (If that is possible)
Built in SD card slot (Case would need modding)
Upgraded sound hardware
Something like that which would fit into the A1200's original casing with very little modding required on the casing would really give an A1200 a modern computer feeling whilst still retaining the original looks.
Obviously same could be designed for the 500, A4000 and so on. Maybe even the A600.