My 2k side is pretty stable. I haven't seen a blue screen since before I started using 2k, which was 2 years ago.
When I worked at a news station we had Dell boxes all running Win2K. We would run AP-ENPS (which is the AP wire), Adobe Premier, and Pathfire. Along with Microsoft Office. BSOD were almost a daily occurance. It seemed the IT people were always having to re-install software or the OS. Granted AP-ENPS would have updates that would seem to mess up Windows so the IT guys would have to get Windows to work with the upgrade. This would screw up Adobe Premier. So the vicious cycle continued. That is until they shut down our news department. Corporate bastards! :-x
I was working in Photoshop at work one day and the computer went into the BSOD for whatever reason. The only thing I was running was Photoshop. :roll:
At home I have a Win2K/Linux Duel Boot (seperate hard drives) and the only problem I've had (so far) is that Win2K started acting screwy when I installed a Logitech Mouse and it's software. Turns out Logitech installed spyware with their driver installation and it was screwing with explorer.