Of cource it will play!!!
I have it on my A600 as a slave HD. I tried booting from it since it works like a regular HD but pretty much faster and quiter.
The only bad thing is the limited write cycles that the CF disks have. I wouldn't recommend of using the CF as a main HD especially if you use your amiga a lot cause after a while you will experience problems and maybe data loss if your miggy crashes. It's perfect though for file transfer with your main PC using UAE!!!
I total recommend it
