Depends on your CPU.
IMO : Upgrades should be in the following order:
1) Hard Drive (or IDE->CF/SD)
2) Amiga->PC Data transfer (External IDE->CF/SD, USB or Networking)
3) RAM
4) CPU
5) RTG
The thing is with the Mediator Route... if you add a 256Mbyte Radeon 92x0 RTG gfx card the memory can be used for the main system so at the same time you're also adding upto ~240Mbytes of Zorro RAM.
Negative side is that you will either need a scandoubler & monitor switcher or two monitors.