Well, only to ZII memory.
Yes I think this is true. A GVP controller with RAM for example has DMA. You must use the memory mask fields in the RDB to constrict the memory the SCSI driver will use.
Obviously this RAM is 16-bit and has a bandwidth limitation when used by a 32-bit CPU.
Some accelerators have their own 32-bit CPU, 32-bit RAM, SCSI controller and DMA controller to overcome these problems. (Cyberstorm for example.)