Although rare the 4000T had advantages but nothing a guy with a 4000 desktop could not achieve. Ive had my 4000D in a tower for years running a VT Flyer system and its been working for most of the time. I think the biggest issue with A4000s in general is the power supplies and failing 3640 boards. I upgraded my 4000s power supply to a standard 700watt ATX and adapted the power connector to fit.
Adding a SCSI controller is easy and the Mediator board give it the ability to mount the cards in correctly for a tower case.
if you have a A4000 with 4091 scsi controller its basically not much difference.
I replace the fan in the 4000 psu's with a higher cfm quiet one usually when i get one.
I find the the 3640's are quite reliable, the biggest thing that causes most people to think they are dead is capacitors(some of which are soldered on with backward polarity) leak on the boards,there are traces running under the caps and the leakage eats the trace. i have repaired dozens of them over the last 20 years with this trouble.
I have overclocked a good few to 35mhz+ and they run fine even in toaster systems.
The Pals on the 3640 are good for 50mhz~.