The other ROM positions (U182, U183) are for ICs that have a different pinout such as the 27C220 and 27C2048.
The standard positions U180, U181 are for pinouts to suit 27C100, 27C200, etc.
You can't have two types of ROMs fitted at once, although if you were to disconnect _ROMEN to each ROM pair and fit a toggle switch so that only one pair can be active at once, then it would be possible to switch between the two. You'd need to add pullup resistors on the ROM _OE lines for when nothing is connected.
But it's a lot nicer use to use a ROM switcher module or BlizKick instead of chopping the hardware around.
Are you sure about the type of roms the 2 sockets can use? I know the 27c220,2048 etc can replace the rom tower(which used 27c200,400 etc) on the rev 7 boards direct(u180,181) eliminating it ,but i seem to recall i tried the 27c220/2048 etc in the u182,u183 positions and it did not work. My memory may be failing me but those sockets don't seem to work for any rom/eprom pinouts i found.
Have you actually used those sockets?
Mech