Of course "reasonable" in this case is pretty small. I'm sure the Replay board will be outselling them with a very high factor (not least because it's open and will come with a bunch of cores for other classic computers as well), for example. The Natami is catering for a very specific niche.
Yes as the owner of a BlizzzardPPC/060 equipped A1200 Tower with a mediator, subway and a hole lot of other addons, I can say that I now use my Sam440 and Minimig more mainly because they are both more stable solutions probably down to the ageing of my A1200 hardware.
But nether completely replaces my A1200 setup which I still use from time to time but in combination they come very close do doing just that for me.
And if and when my ageing 060 card fails I will probably look at replacing the A1200Tower with FPGA solution that gives me good AGA, CGX support network support and 040 or better levels of 68k performance, but I am not looking for a new hardware solution this year.
I do have to say though that my minimig feels like a real A500 for playing games on in a way that WinUAE and UAE on my sam440 just cant beat, thats not to say that I dont like and use WinUAE as well, it just feels different.