there are no fixed rules about what kind of processor can be used with an amiga. anything can be used as long as you interact them with proper bus handling. The reason why there are no 060 accelerators for A500 is simply because no one made them, because A500 being the low end of the amiga line, people not being able to afford even and a1200 most probably will never buy a 060 board for a500.
also 68000 bus (A500) and 68020 (a1200) are different in that it is more easy for a1200 to interact with a 68040 bus I belive. But it is possible as there are 68060 boards for A2000, which is a 68000 bus. Theoratically, you can run a PPC accelerator on an A500 with Zorro2 bus expansion, blizzard 2060, PPC developer board.