Well, it's possible... But quite a bit of work.
Don't forget that there a various 8375s around, one for 1 MB chip (replacement for older 8370/71), one for 2 MB in A3000 (32 bit chip RAM), one for A600/500+.
Take a look at the table in the German Wikipedia
article where the variants are compared and choose one of them. There are a couple of changes to be done to the PLCC socket (rerouting of traces) - nothing the simple onboard 1 MB expansion compares to - and a MegAchip is a much simpler solution. Or just get an A500+.