years ago (like in the late 80's) Rose and Doug Lovell (R&D L Productions) used the Summagraphics table (seriel port) and wrote their own driver. It was like having a second mouse so it worked no matter what the OS was. I remember being able to use it with OS3.5 and 3.9
Of course, those tablets are no longer being made. There was some sort of tablet before that but it was kinda "cheap". The summagraphics had a stylus with two buttons so you could emulate both mouse buttons. It was great for use with DPaint and their (R&D L) LightBox software.
a little Amiga history lesson :-D