NEVER PLUG OR UNPLUG ANYTHING ON A CD32 WHILE IT'S TURNED ON!!!
That's how you blow up your audio capacitors and start a whole bunch of other problems. The same thing goes for A1200s!
Good advice that would be very wise to follow (skilgannon). As Save2600 stated it is very well documented that the mouse and joystick ports can be easily blown if removal and/or installing to those ports while the power is on.