I read that putting in a 68010 was not worth the effort because not all programs were compatible.
So which programs were not compatible?
Back in the days when I still used my A500 I also ran it with an 68010. AFAIR all I noticed was a slight acceleration - I cannot remember ever having encountered an incompatible program.
But I used the A500 mainly for serious tasks - I was never focussed on games. Maybe there were incompatible games - IDK.
All my productivity software (Office, CAD, CNC) ran fine.