Gfx. Games.
You'll have to look hard for a game with even half those requirements without resorting to boring PC ports. I'm sure that there's a huge market who wants play sub-par ports of old PC games and use OWB in slow motion on these boards...
What kind of graphic work would you do? Raytracing spheres over checkerboards in 5000 x 5000 AGA? Spinning chrome logotype animations over grid pattern in 1080p?

Please be more specific, and as I said, more realistic! 68k in the high end memory range is a niche market, and I frankly don't see why anyone would go that route just to be able to do in 1/100th of the quality and speed what any sane person would do with a modern computer. I don't think that a 68k Amiga has anything to catch up to when it comes to modern computers... they're different fruit!