Did you happen to accidentally short any pins on the 1488/1489 when you were measuring? This can apply +/-12V on the 5V only CIA inputs which can damage the CIA.
Or it could be that old problem of poor contact in the IC sockets. Removing then reinserting the IC will scrape oxidisation from the contact surfaces and can temporarily/permanently fix the contact problems.
Swap the CIAs back again, if the non-booting problem returns, then most likely you have a faulty CIA (8520).
Did you make any progress with the serial diagnostics? The 1488/1489 should not normally get very warm.
At this point your repair options are:
1. Measure what's going on as described to work out where the problem is.
2. If you can't do this or don't have the test instruments, send it to someone who can do it for you.
3. Blindly replace parts until the problem is fixed.
I'm picking you're having trouble with the hardware diagnostics since you didn't report back with anything useful. If you measured 24V across the 1488 (between pins 1 and 14) then the +/-12V supplies are OK.
Replacing the 1488/1489 could be a simple option as they're cheap and easy to get, and also the most likely to receive damage. You'll need someone with good soldering experience to avoid making a mess of it.
If the part has been replaced as you say, and if someone has done a bad job, there could have been PCB damage or damaged tracks or solder shorts. The damage may not be something you'll be able to easily see, but check carefully on the top and bottom side of the board.
It's much less likely to be a Paula/8364 fault. But if you have an A500 spare, you can swap the 8364 and 8520s until you work out which ICs have problems or not.
Else just send the board to someone to repair. A repair job this simple is typically a few minutes work. There's myself in NZ and there are various others around the planet who can do the same.
Not sure but don't think. One of the CIA chips were dead then I replaced it with a new one.
The replaced 1488 was working fine before until AExplorer crashed and transmit stopped working, then not PCB damage.
I replaced 1488 again but it didn't help. I may replace Paula next time.
According to this, 1488 is responsible for transmit not 1489, right?
1. Modem will not transmit. Most likely causes are:
o 1488 U38 (transmit) (U304 A2000)
o 8364 U3 Paula (U200 A2000)
o 8520 U8 Even CIA (U301 A2000)
2. Modem or serial port will not receive:
o 1489 U39 (receive) (U305 A2000)
o 8364 U3 Paula (U200 A2000)
o 8520 U8 Even CIA (U301 A2000)