Another suggestion for when using big disks (over 4Gb) is to use the
PFS3 disk filing system.
It supports disks up to 3Tb in size, is much faster than other
filesystems I've tried, virtually bullet proof and it has heaps of
nice features.
It's a commercial product, but is still available.
If you don't want to spend much, chuck a wanted add on
www.amibench.org