The capacitors which generally leak are the 22µF and 4.7µF ones, which aren't involved in AC decoupling of the 5V supply. The positions they're in are unlikely to damage the left mouse button line due to localised corrosion.
CIA U350 does read the left mouse button, but an intermittent CIA failure like this is not common.
Measure between the left button pin (CN975 pin 6) and U350 pin 10. Should be about 47 ohms if it's working normally. If it's open circuit, then I'd start looking for a problem with a fractured pin in CN975 (which is fairly common), or a crack in resistor ER976.
To check for a cracked connector lead, heat the bottom side soldered connection of the pin. If the pin moves very easily, or slides out when you pull it gently with tweesers, it's obvoiusly broken. Easy enough to fault find/repair.