I would not suggest trying this combo at on a Blizzard SCSI.
MY Blizzard SCSI module burned up... The worst smell in the world.
I don't have a pic at the moment but I can take one tomorrow after my phone recharges.
Anyway, the red/orange component under bottom left of the scsi chip burned almost completely off. Don't know if it is repairable.
http://amiga.resource.cx/photos/blizzardscsi4,4
Just the way it went down, I'm fairly certain it was "25-pin Female DSub to 50-way" that caused the problem and probably not the SCSI2SD but who knows.
Just FYI,
I had a DKB RapidFire SCSI controller that had a blown Zener diode when I obtained it, along with the 2000 it came in. Acill was able to fix it, even though it had burned one of the pads off. He also replaced all the SMD caps on it while servicing it.