I'm using Debian (occasionally). I like the aptget system; its ease-of-use. I tried suse years ago, and was frustrated with the fact that NONE of the programs I tried to compile (and 99% of them required compiling) would work. Even if they did, they depended on other-non-installed-software.
I had to waste some time configuring Debian. Biggest problem (on ANY LINUX/UNIX) for me was damn FONTS. Because of Adobe copyright you need to recompile the font software so that you enable real hinting with nonantialiased fonts. Some people like aliasing fonts but sadly I'm used to Windows and anyways sharper text is easier to read.
BTW, my first problem was mouse: " edit XF86Config-4, Section "InputDevice" /dev/psaux "
configuring APT to work with active FTP and HTTP proxy took some time, as well as SAMBA for file and printer stuff.
but it was fun..
:-)