Normally no.
But, take care !
Use only the floppy PC connector (you'll lack the -12v for sound/uart...), not the "normal" Amiga PS connector.
But do you power it up by the Mediator ?
If yes, you don't have to change your power connection.
Some of the 1st BPPC firmware release didn't have "boot screen menu"... use the lastest firmware upgrade.
