Ordinary Amiga programs would not benefit from the Cybersound driver. There where just a few program written for Cybersound as far as I know.
However, if you install AHI you can use the Paula driver and chose 14bit HIFI and then all AHI powered programs would playback in 14bit. The driver for AHI makes use of the calibration file but the 14bit.driver you can crap.
Please, note that 14bit playback requires some CPU power. On a 040 or better system the performance loss is neglectable, but on a 020 it might be dead slow. (Everything is relative ofcourse!)