68 and 80pin drives are UWSCSI (16bit wide datatransfers) compared to
the 50pins which usually are FASTSCSI (8bit wide datatransfers).
I would guess that many UWSCSI drives only works on UWSCSI
controllers. So get a 68pin controller card!
When using UWSCSI drives you have to use active terminators at the
cable ends. (Note, a cable has two ends)
If you use a 68 to 50pin converter, ensure that it terminates those
datalines that are not wired through.
You know you have terminated your system properly when you spent about
100$ in scsi utilities. :-D