Some facts:
- CV643D optional scan doubler module doesn't work with non-AGA amigas (and it's only a scan doubler...no flicker fixing ability)
- Picasso IV has a built-in multi-compatible SD & FF module (meaning works with any Amiga display chipset)
- Picasso IV requires breakout cables so that the SD/FF part could be cut off (yep, don't laugh) and inserted away from the rest of the card into the video slot which is on the other side of the motherboard, that is if used in A2000. For other Amigas like 3000 and 4000 this is not necessary as the video slot is aligned with a zorro slot.
- CV643D is overall a cheaper option. Picasso IV is guaranteed to be pricey.
- CV643D's 3D part is a joke performance and ability wise... :-)