I helped out a guy a couple of weeks ago; he had just bought an Blizzard060 and SCSI controller, but when he started his computer up, then it always gave him an error requester. I can't remember of it was #80000004 or #80000008, but anyway, the computer didn't function as it should.
I told him to run a viruschecker on his harddrive; that cleared the problem.
It doesn't help you with your diskdrive though, but maybe it's a combo of virus on hdd and a broken diskdrive.
Have you tried hooking the CD drive up to the Amiga once again, and see if it helps? Or without the CD drive; is the scsi chain terminated?