If we lived near I would show you my settings as described in the link i posted, I've done my fare share of side by side comparisons demonstrations (Sam+my trusty A2000 underneath) you would be surprised...(Chuck Rock, R-Type, Xenon 2 and more no difference whatsoever running side by side and played with the same joystick, a competition pro standard + USB version).
I've used UAE quite some bit (I use it for development), so I'm aware that's it's pretty ok. But still, nothing beats the real thing. And emulation (UAE and launchers) in itself is nothing AOS4-specific, so all the benefits are also available on other platforms (and especially on Windows with it's superior WinUAE).